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Preview: Buffalo Bills vs Los Angeles Chargers — Sep 27

The Buffalo Bills prepare to host the Los Angeles Chargers in an upcoming NFL matchup scheduled for Sunday, September 27, 2026, at 5:00 PM UTC.

Heading into this fixture, the Bills sit strong with a 2-0 record, currently holding the number two seed in the American Football Conference. Meanwhile, the Chargers look to turn their season around as they sit at 0-2 and occupy the 15th seed in the conference standings.