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NFL Week 6 last-minute best bets: Panthers beat up on banged-up Eagles, Bucs beat Steelers

The Carolina Panthers enter Week 6 with a clear advantage over the Philadelphia Eagles, who are battling a wave of injuries that has left their roster severely depleted. The Eagles will take the field without starting quarterback Jalen Hurts, who is sidelined by a blood clot in his calf, handing the reins to backup Tanner McKee for his first meaningful action in the NFL.

The absence of star running back Saquon Barkley, out with a hamstring issue, further weakens Philadelphia’s offense, while the Panthers arrive rested after a bye week, giving them a significant edge in both health and preparation. Despite the Eagles’ star power, including top wideout DeVonta Smith, the Panthers are favored to pull off the upset in a matchup where rest and roster depth could decide the outcome.

Meanwhile, the Tampa Bay Buccaneers look to continue their strong start with a showdown against the Pittsburgh Steelers, who have struggled to find consistency this season. The Bucs’ depth and experience could give them the edge, especially if they can capitalize on any defensive lapses from a Steelers team still searching for its rhythm.

With both games offering compelling storylines, Week 6 promises high-stakes drama for fantasy players and bettors alike.

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