14 more NFL Week 1 games, 14 matchup previews: We have predictions, picks and wild stats
The opening week of the 2026 NFL campaign features fourteen upcoming contests following earlier showdowns involving Seattle beating New England and the Rams facing San Francisco. Prominent fixtures on the schedule include Buffalo battling Houston, Baltimore taking on Indianapolis, Green Bay visiting Minnesota, and Dallas meeting the Giants, before wrapping up Monday night when Kansas City hosts Denver.
The slate highlights marquee passer face-offs like Josh Allen against C.J. Stroud, alongside running back duels featuring Derrick Henry and Jonathan Taylor, while several players such as Jared Verse, Tua Tagovailoa, David Montgomery, Kyler Murray, and Kirk Cousins make their debuts with new squads.
Ahead of Sunday's Buffalo-Houston clash—where the visiting Bills enter as 1.5-point favorites with an over/under set at 44.5—pass rusher Bradley Chubb noted that the defense anticipates diverse offensive packages and a strong rushing attack from the Texans following their offseason additions. Analysis and projections across the entire slate integrate input from NFL Nation reporters, statistical forecasts via ESPN Research and the Football Power Index, bold outlooks from Seth Walder, viewing considerations from Ben Solak, fantasy updates from Eric Moody, and betting guidance courtesy of Pamela Maldonado.
