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Week 2 of the NFL season features a Thursday clash between the Buffalo Bills and the Detroit Lions, marking the inaugural game at the new Highmark Stadium. Both squads carry 1-0 records, with Buffalo coming off a 36-31 triumph over the Houston Texans and Detroit edging the New Orleans Saints 31-30.

The Bills feature new top receiving target DJ Moore alongside quarterback Josh Allen, while head coach Dan Campbell seeks to elevate the Lions beyond the 9-8 record they produced a year ago. 5 points, while promotional deals offer up to $350 in wagering incentives for players staking $5 or more across seven consecutive days.

5-point underdog. The meeting brings head coach Lane Kiffin back to Oxford following his exit to LSU right ahead of the Rebels' playoff push, an absence Ole Miss weathered by advancing to the national semifinals.