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NFL Week 5 injury report: Lamar Jackson, Ja'Marr Chase among several stars uncertain for Sunday

Week 5’s injury roundup shows a growing list of marquee players on the sidelines, with Baltimore’s Lamar Jackson and Cincinnati’s Ja’Marr Chase among the uncertain names after exiting their Week 4 games early. Saquon Barkley, Tee Higgins and Rashee Rice also left their contests, adding to a string of offensive casualties that has already sidelined quarterbacks Jaxson Dart (season‑ending), Jayden Daniels, Caleb Williams, Baker Mayfield, Sam Darnold and Kyler Murray at various points this season.

The Chiefs and Panthers will use their Week 5 byes to recover, while the Rams travel to face the Bills on Monday Night Football and skip Wednesday practice. The Buccaneers are without starter Baker Mayfield (thumb) and have secondary losses in Benjamin Morrison (quad) and Antoine Winfield Jr.

(rib fracture), prompting a second‑straight start for Jalon Daniels. Dallas lists several defensive hamstring issues and a questionable status for lineman Tyler Smith.

Philadelphia’s roster heads to London with Saquon Barkley (hamstring) and multiple defensive players sidelined, and Chicago enters its matchup against Green Bay without Caleb Williams (hamstring) and running backs Kyle Monangai and D’Andre Swift.

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