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College Football Sees Major Quarterback Developments Ahead of Week 7 Matchups

Major quarterback developments are shaping key college football matchups ahead of Week 7. Tennessee head coach Josh Heupel announced that George MacIntyre will start at quarterback for the second straight week against Alabama on October 17, 2026.

MacIntyre previously started in Tennessee's game against Arkansas. Faizon Brandon, who was benched the week before the upcoming game, remains on the injury report for the Volunteers ahead of the matchup.

The game between Tennessee and Alabama highlights a Week 7 schedule featuring six ranked matchups. Ranked in the top 25, the Tennessee Volunteers enter the game as 7.5-point favorites against No. 6 Alabama, with the over/under set at 53.5 points.

Other top matchups this week feature No. 5 Indiana hosting No.

4 Ohio State. Indiana holds a 6-0 record this season following a 20-17 victory at Nebraska on October 10, 2026.

This game serves as a rematch of the 2025 Big Ten Championship Game, which Indiana won 13-10. Ohio State brings a 5-1 record into the contest, with its single defeat coming in a 24-23 loss at Texas on September 12, 2026.

Ohio State is listed as a 3.5-point road favorite with an over/under of 50.5 points. Additionally, No.

8 BYU travels to face No. 2 Notre Dame, where Notre Dame is favored by 10.5 points with an over/under of 48.5 points.

Roster changes are also affecting other Week 7 contests. Washington Huskies quarterback Demond Williams Jr.

will miss the game against Purdue due to injury. Elijah Brown will take over the starting duties after completing 28 of 39 passes for three touchdowns in relief of Williams against Iowa.

Washington enters the game on a three-game losing skid, which includes a 41-24 defeat against Iowa on October 10, 2026. Purdue defeated Washington 49-13 in their previous meeting in 2025.

Purdue enters the matchup as a 3-point home favorite over Washington, with the over/under line set at 50.5 points. The Purdue offense features running back Fame Ijeboi, who ranks 20th nationally in rushing yards after accumulating 549 yards on the ground this season.

This report also draws on coverage from CBS Sports, Fox Sports.

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