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College football odds, lines, schedule for Week 7: Notre Dame opens as favorite in top-10 battle at BYU

Notre Dame faces its toughest challenge of the season when it travels to Provo, Utah, for a Week 7 showdown against BYU, a game that could be pivotal for both teams’ College Football Playoff hopes. The Fighting Irish, favored by 11.5 points in early lines, enter as the higher-ranked team but will play in front of a hostile crowd, marking their first meeting with BYU in 22 years and the first time both squads are ranked in series history.

For BYU, a win over Notre Dame would significantly bolster their resume, especially given the Big 12’s limited high-profile matchups outside the conference championship. Meanwhile, the week’s slate includes another top-10 clash as Ohio State returns to Indiana for a rematch of last year’s Big Ten title game, with the Buckeyes aiming to extend their strong start since a midseason setback.

Elsewhere, Missouri and Ole Miss renew their SEC rivalry, featuring a quarterback showdown between Austin Simmons and Trinidad Chambliss in a game that could impact both teams’ playoff aspirations.

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