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Week 3 NFL odds, picks, predictions: Computer model backs Lions and 49ers

Ahead of the Week 3 slate, an advanced computer simulation has evaluated every upcoming matchup following extensive travel considerations. Notably, the schedule features a historic international contest taking place in South America, where the Dallas Cowboys will serve as the designated home team against the Baltimore Ravens in Rio de Janeiro.

Elsewhere across the league, other travelers face distinct challenges during their early window matchups. The Los Angeles Chargers hit the road to meet the Buffalo Bills, while the Seattle Seahawks travel to face the Washington Commanders amidst injury concerns for opposing quarterback .